Lipids and Lipid Derivatives
Medchemexpress LLC Estrone (Standard) | 53-16-7 | 99.7% | 100 MG
Estrone (Standard) serves as an analytical standard for research and analytical applications. Estrone (E1) is a natural estrogenic hormone, representing a main endogenous estrogen produced by various tissues, particularly adipose tissue. Its formation occurs through the aromatization of androstenedione in fat cells.
- Used in qualitative, quantitative, and methodological research experiments
- Applications include HPLC, GC, and MS
- Appears as a white to off-white solid
- Functions as an analytical reference standard
- For research use only
Apexbio Technology LLC Estrone 53-16-7 10mM (in 1mL DMSO)
Estrone (53-16-7) is a naturally occurring estrogen that modulates estrogen receptor-mediated signaling pathways It is primarily synthesized in ovarian and adipose tissues and participates in the regulation of estrogen-dependent cellular and physiological processes Estrone exerts its biological activity primarily through binding and activating estrogen receptors Experimental model activity type and key metric (IC50/EC50) are not specified Based on these pharmacological properties estrone holds research potential in studies of estrogen receptor activation reproductive endocrinology menopausal hormone transitions and estrogen-dependent signaling pathways and diseases
Sigma Aldrich Fine Chemicals Biosciences Estrone European Pharmacopoeia (EP) Reference Standard | 53-16-7 | MFCD00003620 |
Estrone European Pharmacopoeia (EP) Reference Standard | Mol Wt: 270.37 | 53-16-7 | MFCD00003620 |
Medchemexpress LLC Estrone (Standard) | 53-16-7 | 99.7% | 50 MG
Estrone (Standard) is the analytical standard of Estrone, a natural estrogenic hormone (E1) produced by various tissues, particularly adipose tissue. It is intended for research and analytical applications, resulting from the aromatization of androstenedione in fat cells.
- Used as a reference standard assay
- Utilized in qualitative, quantitative, and methodological research experiments
- Commonly used in HPLC, GC, and MS applications
Medchemexpress LLC Estrone-13C3 | 1241684-29-6 | 98.0% | 1 MG
Estrone-13C3 is the 13C-labeled version of Estrone, a naturally occurring estrogenic hormone. It is a primary endogenous estrogen, synthesized in various tissues through the aromatization of androstenedione. This compound is suitable for research use as a tracer and as an internal standard for quantitative analysis.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Apexbio Technology LLC Ethinyl Estradiol 57-63-6 500mg
Ethinyl Estradiol (57-63-6) is a small-molecule estrogen receptor agonist targeting intracellular estrogen receptors It is designed to activate these receptors thereby regulating transcription of estrogen-responsive genes and influencing reproductive biology and cell proliferation pathways Ethinyl Estradiol exerts its biological activity primarily through direct binding to estrogen receptors leading to the modulation of endocrine-regulated mechanisms Based on these pharmacological properties Ethinyl Estradiol holds research potential in studies of receptor-mediated responses endocrine regulation mechanisms synthetic hormone interactions drug interactions contraceptive mechanisms and hormone-dependent physiological processes
Medchemexpress LLC Estradiol-d2-1 | 3188-46-3 | 1 MG
Estradiol-d2-1 is a deuterium-labeled Estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. It upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules
- Has potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Alpha-Estradiol (Standard) | 57-91-0 | 99.93% | 25 MG
Alpha-Estradiol (Standard) is the analytical standard of Alpha-Estradiol, intended for research and analytical applications. It is a weak estrogen and a 5α-reductase inhibitor used as a topical medication in the treatment of androgenic alopecia.
- Reference standard supplied assay
- Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS
Medchemexpress LLC Estradiol enanthate | 4956-37-0 | 98.1% | 1 ML
Estradiol enanthate (E2EN) is a shorter-acting estrogen. It is an injectable contraceptive when combined with Dihydroxyprogesterone acetophenide. Estradiol enanthate promotes withdrawal bleeding, similar to menstruation. It is for research use only and not sold to patients.
- Molecular weight: 384.55
- Formula: C25H36O3
- Appearance: Solid
- Color: White to off-white
- SMILES: C[C@@]12[C@@H](OC(CCCCCC)=O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])CC2
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture and light; In solvent: -80°C for 6 months, -20°C for 1 month (sealed storage, away from moisture and light)
- Solubility (In Vitro): DMSO: 125 mg/mL (325.06 mM; requires ultrasonic; hygroscopic DMSO impacts solubility, use newly opened DMSO); Ethanol: ≥ 100 mg/mL (260.04 mM)
Medchemexpress LLC Prt062607 (acetate) | 1370261-98-5 | C21H27N9O3 | 50 MG
PRT062607 acetate is a chemical compound suitable for laboratory use and the manufacture of substances. This product is stable under recommended storage conditions and is not classified as a hazardous substance or mixture. It is provided in solid form and is intended for research use only.
- Solid appearance
- Stable under recommended storage conditions
- Not classified as a hazardous substance or mixture
- Intended for research use only
- Recommended storage at 4°C, sealed, away from moisture
Medchemexpress LLC JMV 449 acetate | 141863-45-8 | 99.7% | 807.03 | 10 MG
JMV 449 acetate is a potent neurotensin receptor agonist. It shows an IC50 of 0.15 nM for inhibition of 125I-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. It also has highly potent and long-lasting hypothermic and analgesic effects in the mouse.
- Potent neurotensin receptor agonist
- IC50 of 0.15 nM for inhibition of 125I-neurotensin binding to neonatal mouse brain
- EC50 of 1.9 nM in contracting the guinea-pig ileum
- Highly potent and long-lasting hypothermic and analgesic effects in the mouse
Medchemexpress LLC CGGK acetate | 96.78% | 363.43 (free acid) | 1 MG
CGGK acetate is a control peptide of CAQK peptide, intended for research use only. It presents as a white to off-white solid with a purity of 96.78% and a molecular weight of 363.43 (free acid). Its chemical formula is C13H25N5O5S.xC2H4O2. This product is shipped at room temperature and requires sealed storage, away from moisture.
- Sequence: Cys-Gly-Gly-Lys
- Purity: 96.78%
- Solubility in DMSO: ≥ 100 mg/mL
- Powder storage: -80°C for 2 years, or -20°C for 1 year
- In solvent storage: -80°C for 6 months, or -20°C for 1 month
Medchemexpress LLC AKN-028 acetate | 98.4% | 362.39 | 50 MG
AKN-028 acetate is a novel tyrosine kinase (TK) inhibitor. It is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. It inhibits FLT3 autophosphorylation and induces a dose-dependent cytotoxic response (mean IC50=1 μM). It also induces apoptosis by activation of caspase 3. AKN-028 acetate can be used in research of acute myeloid leukemia (AML).
- Novel tyrosine kinase (TK) inhibitor
- Potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM
- Inhibits FLT3 autophosphorylation
- Induces a dose-dependent cytotoxic response (mean IC50=1 μM)
- Induces apoptosis by activation of caspase 3
- Can be used in research of acute myeloid leukemia (AML)
- Inhibits growth of primary AML and MV4-11 cells in mice